127 Hours, director Danny Boyle's film about Aron Ralston trapped in a Utah canyon, opens this Friday, November 5. James Franco plays the trapped hiker/climber.
I only saw a slightly extended trailer back in August at Outdoor Retailer, but there's a lot of good buzz and anticipation around the film (just check out all those glowing quotes on the official movie site).
Apparently the self-amputation scene is intense and not for the faint of heart. Reports of people fainting at screenings appear in the Los Angeles Times.
Movie buffs can read Vanity Fair's interview with Boyle, Franco, and Ralston discussing the film.